DYNAMICS OF RENAL FIBROSIS MARKERS IN PATIENTS WITH CHRONIC HEART FAILURE
Keywords:
chronic heart failure, collagen IV, glomerulosclerosis, renal fibrosis, chronic kidney disease, proinflammatory cytokine, Tumor necrosis factor‐alpha.Abstract
Determination of collagen IV in urine sediment and pro-inflammatory cytokine tumor necrosis factor‐alpha (TNF-α) in the blood for the purpose of early detection of sclerotic processes in the glomerular membrane of the kidneys in patients with chronic heart failure (CHF).
References
Cohen MP, Lautenslager GT, Shearman CW. Increased urinary type IV collagen marks the development of glomerular pathology in diabetic d/db mice. Metabolism. 2001 Dec;50(12):1435-40. doi: 10.1053/meta.2001.28074. PMID: 11735089.
European Journal of Heart Failure 2020, Volume 22, Issue 12.
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1789-1858. doi: 10.1016/S0140-6736(18)32279-7.
Groenewegen A, Rutten FH, Mosterd A, Hoes AW. Epidemiology of heart failure. Eur J Heart Fail. 2020 Aug;22(8):1342-1356. doi: 10.1002/ejhf.1858.
Jefferson JA, Alpers CE, Shankland SJ. Podocyte biology for the bedside. Am J Kidney Dis. 2011 Nov;58(5):835-45. doi: 10.1053/j.ajkd.2011.03.033.
Kim, Y.H., Goyal, M., Kurnit, D., et al. (2001) Podocyte Depletion and Glomerulosclerosis Have a Direct Relationship in the PAN-Treated Rat. Kidney International, 60, 957-968.https://doi.org/10.1046/j.1523-1755.2001.060003957.
Okonogi H, Nishimura M, Utsunomiya Y, Hamaguchi K, Tsuchida H, Miura Y, Suzuki S, Kawamura T, Hosoya T, Yamada K. Urinary type IV collagen excretion reflects renal morphological alterations and type IV collagen expression in patients with type 2 diabetes mellitus. Clin Nephrol. 2001 May;55(5):357-64.
Panchapakesan U, Pegg K, Gross S, Komala MG, Mudaliar H, Forbes J, Pollock C, Mather A. Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy? PLoS One. 2013;8(2):e54442. doi: 10.1371/journal.pone.0054442.
Patrakka J, Tryggvason K. New insights into the role of podocytes in proteinuria. Nat Rev Nephrol. 2009 Aug;5(8):463-8. doi: 10.1038/nrneph.2009.108. Epub 2009 Jul 7. PMID: 19581907.
Schiffer M, Bitzer M, Roberts IS, Kopp JB, ten Dijke P, Mundel P, Böttinger EP. Apoptosis in podocytes induced by TGF-beta and Smad7. J Clin Invest. 2001 Sep;108(6):807-16. doi: 10.1172/JCI12367. PMID: 11560950; PMCID: PMC200928.; Kim YH, Goyal M, Kurnit D. 2001
Shankland SJ. The podocyte’s response to injury: role in proteinuria and glomerulosclerosis. Kidney Int. 2006 Jun;69(12):2131-47. doi: 10.1038/sj.ki.5000410.
Lakshmi Srinivasan, Laurie E. Kilpatrick Cytokines and Inflammatory Response in the Fetus and Neonate, inFetal and Neonatal Physiology (Fifth Edition), 2017
