CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF CHILDREN WITH COVID-19 DUE TO CYSTIC FIBROSIS

Authors

  • Nodir Fazliddinovich Ruzimurodov Institute of Human Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan
  • Tamara Uktamovna Aripova Institute of Human Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan
  • Diloram Abdullaevna Musakhodjayeva Institute of Human Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan
  • Batir Bakhromovich Mirzaev Institute of Human Immunology and Genomics of the Academy of Sciences of the Republic of Uzbekistan, Tashkent, Uzbekistan

Keywords:

cystic fibrosis, COVID-19, cytokine, immunology.

Abstract

The study of clinical and immunological characteristics of children with COVID-19 against the background of cystic fibrosis is becoming highly relevant in light of the pandemic. Cystic fibrosis, as a chronic disease, poses special challenges to the immune system, which makes patients in this group vulnerable to the SARS-CoV-2 virus.

References

Bodas M, Vij N. Adapting proteostasis and autophagy for controlling the pathogenesis of cystic fibrosis lung disease. Front Pharm. 2019;10:20.

Colombo C, Burgel PR, Gartner S, van Koningsbruggen-Rietschel S, Naehrlich L, Sermet-Gaudelus I, et al. Impact of COVID-19 on people with cystic fibrosis. Lancet Respir Med. 2020;8:e35–e36.

Cosgriff R, Ahern S, Bell SC, Brownlee K, Burgel PR, Byrnes C, et al. A multinational report to characterise SARS-CoV-2 infection in people with cystic fibrosis. J Cyst Fibros. 2020. https://doi.org/10.1016/j.jcf.2020.04.012.

Flight WG, Bright-Thomas RJ, Tilston P, Mutton KJ, Guiver M, Morris J, et al. Incidence and clinical impact of respiratory viruses in adults with cystic fibrosis. Thorax. 2014;69:247–53.

Ornatowski W, Poschet JF, Perkett E, Taylor-Cousar JL, Deretic V. Elevated furin levels in human cystic fibrosis cells result in hypersusceptibility to exotoxin A-induced cytotoxicity. J Clin Invest. 2007;117:3489–97.

Poli P, Timpano S, Goffredo M, Padoan R, Badolato R. Asymptomatic case of Covid-19 in an infant with cystic fibrosis. J Cyst Fibros. 2020. https://doi.org/10.1016/j.jcf.2020.03.017.

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Published

2023-10-20

How to Cite

Ruzimurodov , N. F., Aripova , T. U., Musakhodjayeva , D. A., & Mirzaev , B. B. (2023). CLINICAL AND IMMUNOLOGICAL CHARACTERISTICS OF CHILDREN WITH COVID-19 DUE TO CYSTIC FIBROSIS. SCHOLAR, 1(28), 381–387. Retrieved from https://researchedu.org/index.php/openscholar/article/view/5069

Issue

Vol. 1 No. 28 (2023): SCHOLAR

Section

Articles

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.